Health Care

Artificial Womb Supports Premature Fetal Lamb Development

Artificial Womb Supports Premature Fetal Lamb Development”

"Currently, there's no way to support these infants without those associated problems", said Alan Flake, a fetal surgeon at CHOP and co-inventor of the device.

Researchers tested the extra-uterine support device and monitored its effects on foetal lambs, in which prenatal lung development is very similar to that occurring in humans. The animals "breathed" and swallowed normally, opened their eyes, grew wool and developed properly functioning nerves and organs, said the researchers in the journal Nature Communications.

A singular womb-like arrangement that has been designed by pediatricians could change the way we look at premature babies in the future.

Flake stressed that the womb-like system is not meant to support premies any younger than today's limits of viability - not what he calls the more "sensationalistic" idea of artificially growing embryos.

"Foetal lungs are created to function in fluid, and we simulate that environment here, allowing the lungs and other organs to develop, while supplying nutrients and growth factors", said foetal physiologist Marcus Davey who designed the psuedo-womb's inflow and outflow system.

"One of the unspoken things in extreme preterm birth is that there are families who say, 'If I had known the outcome for my baby could be this bad, I wouldn't have chosen to put her through everything, '" she said in an interview with the Verge.

The researchers have developed several prototypes of the artificial womb over the past three years, starting off with a glass incubator tank and resulting in the current fluid-filled sac. Just as the fetus is surrounded by the amniotic liquid inside the mom's uterus, the plastic bag-like womb is filled with a liquid which has the same physiological properties as its biological counterpart.

Facebook killer takes his own life as police close in
A $5.35 (£4.17) order of Chicken McNuggets and large fries led police to Facebook killer Steve Stephens after a two-day manhunt. As his vehicle was spinning out of control, Stephens pulled a pistol and shot himself in the head, according to police.

Delhi BJP files police complaint against Kejriwal
There are 13,022 polling stations, of which Delhi Police have deemed 3,284 as sensitive, while 1,464 are hypersensitive. Both, he Aam Aadmi Party and the Swaraj India are in the contention for MCD election for the first time.

Apple Wants To Make Your iPhone A Lot More Eco-Friendly
Additionally, the report also stated that Apple's suppliers have also promised to use renewable energy by end of 2018. The ultimate aim is "to one day end our reliance on mining altogether", said Apple , without settling a date.

The hope is this technology will one day be used to aid development of severely premature babies. The average human gestation period is 40 weeks. This study is yet to be done on humans and the researchers hope for it to be successful, just like the outcome that the fetal lamb had. There are two tubes, one sucking blood out of the infant then running it through an oxygenator and another feeding the blood back into the body. In both systems, infants breathe a simulated amniotic fluid, but in MI, they're not immersed in a bag of fluid.

This way the animal gets oxygen as it would in the womb, through blood, rather than by using its underdeveloped lungs, buying time for the lungs and other organs to grow normally.

"Fluid is very important in terms of fetal lung development", said Flake.

A video further demonstrating the artificial womb's function is included below. In most cases, an infant in an artificial womb would be removed at that stage, to reduce the risks of infection and blood clots that come with the device. It will also need to be down-sized, since human babies are only one-third the size of the lambs used in the study.

Increasingly hospitals attempt to save the most critically premature infants, those born before 26 weeks gestation and even those right at the limits of viability - 22 to 23 weeks.

Flake told reporters that his team is now working with the US Food and Drug Administration to design a preclinical study to further evaluate the safety and efficacy of the system.

Like this


26 April 2017
Stephen Jones says Myles Garrett has physical tools to be great
There's some thought that Cleveland might have to trade ahead of the Jets at No. 6 if they really want the North Carolina QB. Pursue the quarterback only after Garrett is wearing the Browns cap.

25 April 2017
US, Japan, S. Korea envoys discuss N. Korea
Tuesday marks the 85th anniversary of the founding of North Korea's military, a significant date in the country's calendar. The nuclear-powered submarine is built to carry and launch ballistic missiles and Tomahawk cruise missiles.

25 April 2017
Arkansas inmates ask appeals court to review part of ruling
An eighth inmate who had been scheduled to die also won a stay earlier, removing him from the list for April execution. She also noted that the execution team did not have antidotes on hand in case there was trouble with any of the drugs.

25 April 2017
Ivanka Trump heads to Berlin for women's conference
Donald Trump will prioritise the European Union ahead of Britain over free-trade deals with the USA , officials have said . The US president was finally convinced it would be easier than he first thought by Angela Merkel, the newspaper said.

24 April 2017
Moto Z2 Play Images Leak, Show Similar Design to The Z Play
This bump in a battery is also expected to be present in Moto Z2 play because it affected the sale of Moto Z Play a lot. The 3,510 mAh battery is still larger than the batteries included in some of the most popular flagships.

24 April 2017
Ronaldo urges Real Madrid fans: Stop whistling me!
After all, regardless of who scores the goals, football is all about collective effort. The FC crew discuss Real Madrid fans' treatment of Cristiano Ronaldo.

24 April 2017
Egypt's Sissi visits Saudi Arabia as tensions ease
Awad Al-Awad was named minister of culture and information, another key position in the government, replacing Adel Al-Toraifi. Minister of Telecommunications and IT Mohammed Al-Suwaiyel has been replaced by Abdullah bin Amer Al-Sawaha.

22 April 2017
Moto E4 stops by Geekbench to have some specs exposed
The USB Type-C port alongside the speaker grille is all located at the bottom edge while the 3.5mm audio jack is located on top. This Moto X (2017 ) should also make a good buy for people who look for a pocket-friendly phone.

22 April 2017
Pats Inks Rusher James White To A 3-Year Contract Extension
He is most known for his game-winning overtime touchdown in Super Bowl LI, but he also had a great game before that short run. The pipeline of Wisconsin running backs are typically north-and-south guys, but White's been a staple in the passing game.

22 April 2017
Top Delhi school student loses control over vehicle ; kills one, injures 2
The driver, a teenager, was with his two classmates when the accident occurred, police said. It has been learned that a case is registered under IPC 304, according to ANI report.